Over 60 years of life-saving research and humane animal care
WNPRC scientist Igor Slukvin and his team used CRISPR to create HIV-resistant immune cells from monkey stem cells — deleting the CCR5 gene the virus needs to infect T cells — producing a renewable, large-scale source of virus-resistant cells for testing new HIV/AIDS immunotherapies in a preclinical primate model.
By Casey Ostheimer, WNPRC editorial intern The majority of replicating HIV – and its monkey version, simian immunodeficiency virus (SIV) – is found in follicles of the lymphoid tissues; however, most cytotoxic T-lymphocytes, which are the cells that can clear HIV from the body, are not able to reach the follicles. This explains the need …
We are happy to share, thanks to the work of many contributors, archival pdfs of the Gorilla Gazette, a newsletter about gorilla care and conservation created by gorilla keepers at the Columbus Zoo and published from 1987-2013.
By Jordana Lenon Rhesus monkeys at the Wisconsin National Primate Research Center have played a starring role in a study aimed at improving the success of kidney transplants. About 24,000 kidney transplants are performed in the US each year, yet more than 90,000 people are waiting for a transplant. Even when patients get a transplanted …