A dopamineric neuron grown from an induced pluripotent stem cell for Parkinson's disease research by Su-Chun Zhang and Marina Emborg ((S-C Zhang lab photo).

Dopaminergic neuron grown from stem cells by the Emborg and Zhang groups

WNPRC scientific journal articles

Wisconsin National Primate Research Center references are listed courtesy of WNPRC staff and PubMed, National Library of Medicine. If you do not see your publication on this list and it involved the use of center resources in part or in full, please contact Jordana Lenon.


Terasawa E, Garcia JP. Neuroendocrine mechanisms of puberty in non-human primates. Curr Opin Endocr Metab Res. 2020 Oct;14:145-151. Epub 2020 Aug 11.

Martins MA, Gonzalez-Nieto L, Ricciardi MJ, Bailey VK, Dang CM, Bischof GF, Pedreño-Lopez N, Pauthner MG, Burton DR, Parks CL, Earl P, Moss B, Rakasz EG, Lifson JD, Desrosiers RC, Watkins DI. Rectal Acquisition of SIVmac239 Infection Despite Vaccine-Induced Immune Responses Against the Entire SIV Proteome. J Virol. 2020 Oct 7:JVI.00979-20.

Brooks DC, Coon V JS, Ercan CM, Xu X, Dong H, Levine JE, Bulun SE, Zhao H. Brain Aromatase and the Regulation of Sexual Activity in Male Mice. Endocrinology. 2020 Oct 1;161(10):bqaa137.


Majumder A, Suknuntha K, Bennin D, Klemm L, Brok-Volchanskaya VS, Huttenlocher A, Slukvin I. Generation of Human Neutrophils from Induced Pluripotent Stem Cells in Chemically Defined Conditions Using ETV2 Modified mRNA. STAR Protoc. 2020 Sep 18;1(2):100075.

Heffron AS, Lauck M, Somsen ED, Townsend EC, Bailey AL, Sosa M, Eickhoff J, Capuano Iii S, Newman CM, Kuhn JH, Mejia A, Simmons HA, O’Connor DH. Discovery of a Novel Simian Pegivirus in Common Marmosets (Callithrix jacchus) with Lymphocytic Enterocolitis. Microorganisms. 2020 Sep 30;8(10):E1509.

Karino G, Senoo A, Kunikata T, Kamei Y, Yamanouchi H, Nakamura S, Shukuya M, Colman RJ, Koshiba M. Inexpensive Home Infrared Living/Environment Sensor with Regional Thermal Information for Infant Physical and Psychological Development. Int J Environ Res Public Health. 2020 Sep 19;17(18):E6844.

Havton LA, Biscola NP, Christe KL, Colman RJ. Ketamine-induced neuromuscular reactivity is associated with aging in female rhesus macaques. PLoS One. 2020 Sep 21;15(9):e0236430. eCollection.

Abbott DH, Dumesic DA.Fertil Steril. 2020 Sep 9:S0015-0282(20)30778-0. Midgestation origins of androgenic and estrogenic pathophysiology in three major women’s health disorders. Online ahead of print.

Andræ F, Abbott D, Stridsklev S, Schmedes AV, Odsæter IH, Vanky E, Salvesen Ø. Sustained maternal hyperandrogenism during PCOS pregnancy reduced by metformin in non-obese women carrying a male foetus. J Clin Endocrinol Metab. 2020 Sep 1. Online ahead of print.

Cottrell CA, van Schooten J, Bowman CA, Yuan M, Oyen D, Shin M, Morpurgo R, van der Woude P, van Breemen M, Torres JL, Patel R, Gross J, Sewall LM, Copps J, Ozorowski G, Nogal B, Sok D, Rakasz EG, Labranche C, Vigdorovich V, Christley S, Carnathan DG, Sather DN, Montefiori D, Silvestri G, Burton DR, Moore JP, Wilson IA, Sanders RW, Ward AB, van Gils MJ. Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates. PLoS Pathog. 2020 Aug 31;16(8):e1008753.


Toledo NPL, Li H, Omange RW, Dacoba TG, Crecente-Campo J, Schalk D, Kashem MA, Rakasz E, Schultz-Darken N, Li Q, Whitney JB, Alonso MJ, Plummer FA, Luo M. Cervico-Vaginal Inflammatory Cytokine and Chemokine Responses to Two Different SIV Immunogens. Front Immunol. 2020 Aug 25;11:1935. eCollection.

Pedreño-Lopez N, Ricciardi MJ, Rosen BC, Song G, Andrabi R, Burton DR, Rakasz EG, Watkins DI. An Automated Fluorescence-Based Method to Isolate Bone Marrow-Derived Plasma Cells from Rhesus Macaques Using SIVmac239 SOSIP.664. Mol Ther Methods Clin Dev. 2020 Aug 5;18:781-790. eCollection.

Rosen BC, Pedreño-Lopez N, Ricciardi MJ, Reed JS, Sacha JB, Rakasz EG, Watkins DI. Rhesus Cytomegalovirus-Specific CD8+ Cytotoxic T Lymphocytes Do Not Become Functionally Exhausted in Chronic SIVmac239 Infection. Front Immunol. 2020 Aug 12;11:1960. eCollection 2020.

Block LN, Bowman BD, Schmidt JK, Keding LT, Stanic AK, Golos TG. The promise of placental extracellular vesicles: models and challenges for diagnosing placental dysfunction in utero. Biol Reprod. 2020 Aug 28. Online ahead of print.

Li H, Omange RW, Liang B, Toledo N, Hai Y, Liu LR, Schalk D, Crecente-Campo J, Dacoba TG, Lambe AB, Lim SY, Li L, Kashem MA, Wan Y, Correia-Pinto JF, Seaman MS, Liu XQ, Balshaw RF, Li Q, Schultz-Darken N, Alonso MJ, Plummer FA, Whitney JB, Luo M.J Clin Invest. 2020 Aug 27. Vaccine targeting SIVmac251 protease cleavage sites protects macaques against vaginal infection. Online ahead of print.

Curlin J, Schmitt K, Remling-Mulder L, Moriarty R, Goff K, O’Connor S, Stenglein M, Marx P, Akkina R. Evolution of SIVsm in humanized mice towards HIV-2. J Med Primatol. 2020 Aug 10. Online ahead of print.

Zammit M, Tao Y, Olsen ME, Metzger J, Vermilyea SC, Bjornson K, Slesarev M, Block WF, Fuchs K, Phillips S, Bondarenko V, Zhang SC, Emborg ME, Christian BT. [(18)F]FEPPA PET imaging for monitoring CD68-positive microglia/macrophage neuroinflammation in nonhuman primates. EJNMMI Res. 2020 Aug 6;10(1):93.

Kropp Schmidt JA, Mean KD, Puntney RC, Alexander ES, Sullivan R, Simmons HA, Zeng X, Weiler AM, Friedrich TC, Golos TG. Zika virus in rhesus macaque semen and reproductive tract tissues: a pilot study of acute infection. Biol Reprod. 2020 Aug 6: Online ahead of print.

Jaeger AS, Weiler AM, Moriarty RV, Rybarczyk S, O’Connor SL, O’Connor DH, Seelig DM, Fritsch MK, Friedrich TC, Aliota MT. Spondweni virus causes fetal harm in Ifnar1-/- mice and is transmitted by Aedes aegypti mosquitoes. Virology. 2020 Aug;547:35-46. Epub 2020 May 24.

JULY 2020

Snowdon CT, Ziegler TE. Contextual complexity of chemical signals in callitrichids. Am J Primatol. 2020 Jul 9:e23172. Online ahead of print. Review.

Pomplun NL, Vosler L, Weisgrau KL, Furlott J, Weiler AM, Abdelaal HM, Evans DT, Watkins DI, Matano T, Skinner PJ, Friedrich TC, Rakasz EG. Immunophenotyping of rhesus CMV-specific CD8 T Cell Populations. Cytometry A. 2020 Jul 26. Online ahead of print.

Masood F, Farzana M, Nesathurai S, Abdullah HA.Proc Inst Mech Eng H. Comparison study of classification methods of intramuscular electromyography data for non-human primate model of traumatic spinal cord injury. 2020 Jul 1. Online ahead of print.

Ziegler TE, Kulkarni P, Ash H, Cai X, Elizabeth Mayerand M, Rauch B, Ferris CF.J Neurosci Methods. Novel Imaging Technology and Procedures for Studying Brain Function in Preadolescent Awake Marmosets. 2020 Jun 21. Online ahead of print.

Abbott DH, Levine JE, Dumesic DA. Androgen Receptors in Multiple Organ Systems Provide Molecular Gateways to Polycystic Ovary Syndrome? Endocrinology. 2020 Jun 12. Online ahead of print.

Lim SY, Osuna CE, Best K, Taylor R, Chen E, Yoon G, Kublin JL, Schalk D, Schultz-Darken N, Capuano S, Safronetz D, Luo M, MacLennan S, Mathis A, Babu YS, Sheridan WP, Perelson AS, Whitney JB. A direct-acting antiviral drug abrogates viremia in Zika virus-infected rhesus macaques. Sci Transl Med. 2020 Jun 10;12(547).

Ash H, Ziegler TE, Colman RJ. Am J Primatol. Early learning in the common marmoset (Callithrix jacchus): Behavior in the family group is related to preadolescent cognitive performance. Am J Primatol. 2020 Jun 9. Online ahead of print.

Dumesic DA, Abbott DH, Sanchita S, Chazenbalk GD. Endocrine-Metabolic Dysfunction in Polycystic Ovary Syndrome: an Evolutionary Perspective. Curr Opin Endocr Metab Res. 2020 Jun;12:41-48. Epub 2020 Mar 9.

JUNE 2020

Hayashi K, Gonzales TK, Kapoor A, Ziegler TE, Meethal SV, Atwood CS. Development of Classification Models for the Prediction of Alzheimer’s Disease Utilizing Circulating Sex Hormone Ratios. J Alzheimers Dis. 2020 Jun 29. Online ahead of print.

MAY 2020

Kovner R, Souaiaia T, Fox AS, French DA, Goss CE, Roseboom PH, Oler JA, Riedel MK, Fekete EM, Fudge JL, Knowles JA, Kalin NH. Transcriptional Profiling of Primate Central Nucleus of the Amygdala Neurons to Understand the Molecular Underpinnings of Early-Life Anxious Temperament. Biol Psychiatry. 2020 May 19. Online ahead of print.

Finch CL, Crozier I, Lee JH, Byrum R, Cooper TK, Liang J, Sharer K, Solomon J, Sayre PJ, Kocher G, Bartos C, Aiosa NM, Castro M, Larson PA, Adams R, Beitzel B, Di Paola N, Kugelman JR, Kurtz JR, Burdette T, Nason MC, Feuerstein IM, Palacios G, St Claire MC, Lackemeyer MG, Johnson RF, Braun KM, Ramuta MD, Wada J, Schmaljohn CS, Friedrich TC, O’Connor DH, Kuhn JH. Characteristic and quantifiable COVID-19-like abnormalities in CT- and PET/CT-imaged lungs of SARS-CoV-2-infected crab-eating macaques (Macaca fascicularis). bioRxiv. 2020 May 14:2020.05.14.096727. Preprint.

Metzger JM, Lopez MS, Schmidt JK, Murphy ME, Vemuganti R, Emborg ME. Effects of Cardiac Sympathetic Neurodegeneration and PPARγ Activation on Rhesus Macaque Whole Blood miRNA and mRNA Expression Profiles. Biomed Res Int. 2020 May 2;2020:9426204. eCollection.

Aon MA, Bernier M, Mitchell SJ, Di Germanio C, Mattison JA, Ehrlich MR, Colman RJ, Anderson RM, de Cabo R. Untangling Determinants of Enhanced Health and Lifespan through a Multi-omics Approach in Mice. Cell Metab. 2020 May. Online ahead of print.

APRIL 2020

Stener-Victorin E, Padmanabhan V, Walters KA, Campbell RE, Benrick A, Giacobini P, Dumesic DA, Abbott DH. Animal models to understand the etiology and pathophysiology of polycystic ovary syndrome. Endocr Rev. 2020 Apr 20. [Epub ahead of print]

Tavakoli-Tameh A, Janaka SK, Zarbock K, O’Connor S, Crosno K, Capuano S 3rd, Uno H, Lifson JD, Evans DT. Loss of tetherin antagonism by Nef impairs SIV replication during acute infection of rhesus macaques. PLoS Pathog. 2020 Apr 17;16(4):e1008487 [Epub ahead of print]

Goodroe AE, Fitz C, Power ML, Colman RJ, Capuano S 3rd, Ziegler TE. Evaluation of vitamin D3 metabolites in Callithrix jacchus (common marmoset). Am J Primatol. 2020 Apr 9:e23131. [Epub ahead of print]

MARCH 2020

Dumesic DA, Wood JR, Abbott DH, Strauss IJF.  A primate perspective on oocytes and transgenerational PCOS. Reprod Biomed Online. 2020 Mar 7. Online ahead of print.

Martinez-Navio JM, Fuchs SP, Mendes DE, Rakasz EG, Gao G, Lifson JD, Desrosiers RC. Long-Term Delivery of an Anti-SIV Monoclonal Antibody With AAV. Front Immunol. 2020 Mar 17;11:449. eCollection 2020.


Shortreed CG, Wiseman RW, Karl JA, Bussan HE, Baker DA, Prall TM, Haj AK, Moreno GK, Penedo MCT, O’Connor DH. Characterization of 100 extended major histocompatibility complex haplotypes in Indonesian cynomolgus macaques. Immunogenetics. 2020 Feb 29. [Epub ahead of print]

Vermilyea SC, Babinski A, Tran N, To S, Guthrie S, Kluss JH, Schmidt JK, Wiepz GJ, Meyer MG, Murphy ME, Cookson MR, Emborg ME, Golos TG. In Vitro CRISPR/Cas9-Directed Gene Editing to Model LRRK2 G2019S Parkinson’s Disease in Common Marmosets. Sci Rep. 2020 Feb 26;10(1):3447.

Pedreño-Lopez N, Dang CM, Rosen BC, Ricciardi MJ, Bailey VK, Gutman MJ, Gonzalez-Nieto L, Pauthner MG, Le K, Song G, Andrabi R, Weisgrau KL, Pomplun N, Martinez-Navio JM, Fuchs SP, Wrammert J, Rakasz EG, Lifson JD, Martins MA, Burton DR, Watkins DI, Magnani DM. Induction of Transient Virus Replication Facilitates Antigen-Independent Isolation of SIV-Specific Monoclonal Antibodies. Mol Ther Methods Clin Dev. 2020 Feb 13;16:225-237. eCollection 2020 Mar 13.

Haj AK, Breitbach ME, Baker DA, Mohns MS, Moreno GK, Wilson NA, Lyamichev V, Patel J, Weisgrau KL, Dudley DM, O’Connor DH. High-Throughput Identification of MHC Class I Binding Peptides Using an Ultradense Peptide Array. J Immunol. 2020 Feb 14. [Epub ahead of print]

Adriansjach J, Baum ST, Lefkowitz EJ, Van Der Pol WJ, Buford TW, Colman RJ. Age-related differences in the gut microbiome of Rhesus macaques. J Gerontol A Biol Sci Med Sci. 2020 Feb 13. [Epub ahead of print]


Redinbaugh MJ, Phillips JM, Kambi NA, Mohanta S, Andryk S, Dooley GL, Afrasiabi M, Raz A, Saalmann YB. Thalamus Modulates Consciousness via Layer-Specific Control of Cortex. Neuron. 2020 Jan 22. [Epub ahead of print]

Rhoads TW, Clark JP, Gustafson GE, Miller KN, Conklin MW, DeMuth TM, Berres ME, Eliceiri KW, Vaughan LK, Lary CW, Beasley TM, Colman RJ, Anderson RM. Molecular and Functional Networks Linked to Sarcopenia Prevention by Caloric Restriction in Rhesus Monkeys. Cell Syst. 2020 Jan 22. [Epub ahead of print]

Moncla LH, Bedford T, Dussart P, Horm SV, Rith S, Buchy P, Karlsson EA, Li L, Liu Y, Zhu H, Guan Y, Friedrich TC, Horwood PF. Quantifying within-host diversity of H5N1 influenza viruses in humans and poultry in Cambodia. PLoS Pathog. 2020 Jan 17;16(1)  eCollection.

Metzger JM, Matsoff HN, Zinnen AD, Fleddermann RA, Bondarenko V, Simmons HA, Mejia A, Moore CF, Emborg ME. Post mortem evaluation of inflammation, oxidative stress, and PPARγ activation in a nonhuman primate model of cardiac sympathetic neurodegeneration.PLoS One. 2020 Jan 7;15(1) eCollection.

Block LN, Aliota MT, Friedrich TC, Schotzko ML, Mean KD, Wiepz GJ, Golos TG, Schmidt JK. Embryotoxic impact of Zika virus in a rhesus macaque in vitro implantation model. Biol Reprod. 2020 Jan 4. [Epub ahead of print]

More Primate Center References