Congenital heart defects are the most common type of birth defect in the United States and can result in heart failure early in life. Stem cell grafts offer potential as a treatment for cardiac defects, but both laboratory bench experiments and whole-animal studies are necessary for progress in this area. By testing cardiac treatments in …
A new investigational treatment for Parkinson’s disease is showing early promise in its first human clinical trial, thanks in part to foundational work at the University of Wisconsin–Madison and the Wisconsin National Primate Research Center (WNPRC).
WNPRC scientist Marina Emborg and collaborators at Mayo Clinic showed that stem-cell-derived heart muscle cells can safely integrate into the hearts of rhesus macaques — the first congenital heart disease–like monkey model, developed at the Wisconsin National Primate Research Center.
by Jennifer Bal and Mariel Mohns Scientists at the Wisconsin National Primate Research Center (WNPRC) and the Morgridge Institute for Research at the University of Wisconsin–Madison have been at the forefront of stem cell research and regenerative biology since James Thomson isolated the first human embryonic stem cell in 1998. The Thomson Lab continued to pioneer new techniques to advance the field, including methods to …