University of Wisconsin–Madison

Category: Research News

Findings, breakthroughs, publications, new models/methods.

Stem Cells Could Treat Heart Disease

WNPRC scientist Marina Emborg and collaborators at Mayo Clinic showed that stem-cell-derived heart muscle cells can safely integrate into the hearts of rhesus macaques — the first congenital heart disease–like monkey model, developed at the Wisconsin National Primate Research Center.

Bioengineered arteries show promise for cardiovascular surgery

by Jennifer Bal and Mariel Mohns Scientists at the Wisconsin National Primate Research Center (WNPRC) and the Morgridge Institute for Research at the University of Wisconsin–Madison have been at the forefront of stem cell research and regenerative biology since James Thomson isolated the first human embryonic stem cell in 1998. The Thomson Lab continued to pioneer new techniques to advance the field, including methods to …

UW-Madison study in monkeys brings placenta treatment one step closer to humans

In this WPR “Wisconsin Today” conversation, WNPRC scientist Jenna Schmidt and University of Florida collaborator Helen Jones explain how a gene therapy that restores the placental protein IGF-1 — shown safe in rhesus macaques at the Wisconsin National Primate Research Center — could one day treat complicated human pregnancies.

Medicines for Placental Disorders Working Their Way up the Species Ladder

Brain cell grafts in monkeys jump-start human trial for new Parkinson’s treatment

Linde Lee Jacobs brings patient advocacy, personal journey to UW–Madison

By Jordana Lenon Honoring her mother, while helping advance research on frontal temporal dementia (FTD) is Linde Lee Jacobs’ mission. It’s what recently brought her to the University of Wisconsin–Madison, including a visit to the Wisconsin National Primate Research Center. There, she learned about the work of Marina Emborg, professor of medical physics in the …

HIV treatment research advance is published in Science

By Jordana Lenon Findings from a highly collaborative preclinical nonhuman primate study were given the green light to advance to clinical trials for a potential new treatment for HIV. Researchers at multiple institutions, including the Wisconsin National Primate Research Center and led by James Whitney, a virologist at Boston College and Harvard University, published their …

Collaborative efforts among the National Primate Research Centers advance Zika virus research

By Marielle Iannella, editorial intern, Wisconsin National Primate Research Center Zika virus has been circulating in 89 countries around the world, according to a Sept. 1, 2023 report by the Pan American Health Organization. In January 2024, the Bangkok Post reported an uptick of Zika cases in Thailand. Since Zika emerged in the global spotlight …

Why do men and women respond to stress differently? New research suggests answer is found in puberty

A UC Davis–led study, co-authored by a Wisconsin National Primate Research Center researcher, found that testosterone during puberty shapes how the brain responds to social stress differently in males and females.

Combining cell types may lead to improved cardiac cell therapy following a myocardial infarction

UW–Madison researchers, working with the Wisconsin National Primate Research Center and collaborators in Taiwan, showed that combining two types of stem-cell-derived heart cells improves repair of heart muscle after a heart attack — a therapy validated in mice and, crucially, in nonhuman primates at WNPRC