Over 60 years of life-saving research and humane animal care
By Jordana Lenon You may have heard of ceramides as moisture-preserving molecules found in skin, but in the blood stream these molecules may be detectors of early risk for developing metabolic syndrome, a University of Wisconsin–Madison study has found. Ceramides are a type of lipid and they are not only important in keeping skin healthy, …
By Jordana Lenon Lower urinary tract (LUT) dysfunction is prevalent in older adults. Clinical manifestations include urinary retention, incontinence and recurrent urinary tract infections. Bladder catheters and increased risk for infections requiring outpatient antibiotic treatment or hospitalization frequently result. This is often followed by the loss of independence and the need for long-term care in …
Jorge Osorio — a member of WNPRC’s Global Infectious Disease working group and a longtime collaborator on the center’s dengue vaccine and Zika research — has been named to lead the UW Global Health Institute.
WNPRC scientist Igor Slukvin and his team used CRISPR to create HIV-resistant immune cells from monkey stem cells — deleting the CCR5 gene the virus needs to infect T cells — producing a renewable, large-scale source of virus-resistant cells for testing new HIV/AIDS immunotherapies in a preclinical primate model.
By Casey Ostheimer, WNPRC editorial intern The majority of replicating HIV – and its monkey version, simian immunodeficiency virus (SIV) – is found in follicles of the lymphoid tissues; however, most cytotoxic T-lymphocytes, which are the cells that can clear HIV from the body, are not able to reach the follicles. This explains the need …
By Jordana Lenon Rhesus monkeys at the Wisconsin National Primate Research Center have played a starring role in a study aimed at improving the success of kidney transplants. About 24,000 kidney transplants are performed in the US each year, yet more than 90,000 people are waiting for a transplant. Even when patients get a transplanted …
We are excited to share AIMBE’s news release about Marina Emborg, M.D., Ph.D., Professor of Medical Physics and head of the Preclinical Parkinson’s Research Program, based at the Wisconsin National Primate Research Center. Also check out this 2021 Wisconsin Medicine talk by Dr. Emborg. WASHINGTON, D.C.— The American Institute for Medical and Biological Engineering (AIMBE) …
WNPRC scientist Ricki Colman and UW–Madison colleagues showed that aged rhesus monkeys — which develop amyloid plaques naturally as they age — are a promising new model for late-onset Alzheimer’s disease, more closely reflecting the human condition than the young, genetically-engineered mice typically studied.
By Jordana Lenon Understanding whether the severity of maternal and fetal Zika virus infection increases in pregnant women who previously had dengue fever should be a public health priority, according to researchers from multiple universities studying rhesus macaques at the Wisconsin National Primate Research Center. A new study by these researchers is the first to examine …