Shelby O’Connor, PhD

Associate Professor

DEPARTMENTS

Pathology and Laboratory Medicine

CONTACT

Shelby O’Connor’s email
(608) 890-0843

CURRICULUM VITAE

Shelby O’Connor’s Curriculum Vitae

OTHER WEB PAGES

Shelby O’Connor Lab

ALIGNED RESEARCH FOCUS

Infectious disease

ORGAN SYSTEM/DISEASE FOCUS

HIV/AIDS, Tuberculosis, co-infections

RESEARCH DESCRIPTION

My research lab is interested in understanding the host immune response to HIV and the effect that HIV-infection has on host immunity to other pathogens. HIV+ immunocompromised individuals cannot mount robust immune responses like individuals who are otherwise healthy. We use nonhuman primates with defined host MHC genetics to understand key factors of immunity against SIV, a virus closely related to HIV. In addition, we are using nonhuman primates to better understand the role of host genetics in containment of Mycobacterium tuberculosis (Mtb) and the factors that contribute to latent reactivation of Mtb in macaques co-infected with SIV.

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